產(chǎn)品介紹

BD Pharmingen™ Purified NA/LE Hamster Anti-Mouse CD28貨號(hào)： 553294

貨號(hào)： 553294
品牌： BD Pharmingen
Alternative Name:Cd28; CD28 antigen; T-cell-specific surface glycoprotein CD28

Reactivity:Mouse (QC Testing)

37.51

The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T cells, and at even lower density on NK cells. The expression of CD28, in splenocytes and thymocytes,  has been reported to increase after activation. CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast cells. It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes. CD28 is a costimulatory receptor; its ligands include CD80 (B7-1) and CD86 (B7-2). The 37.51 mAb augments proliferation and cytokine production by activated T and NK cells and can provide a costimulatory signal for CTL induction. There is considerable evidence that CD28 is a costimulatory receptor involved in many, but not all, T cell-dependent immune responses.

BD Pharmingen™ Purified NA/LE Hamster Anti-Mouse CD28

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